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TRK Inhibition in TRK Fusion–Positive Lung Cancers

By Alexander Drilon, MD Posted: February 12, 2020 The receptor tyrosine kinases TRKA/B/C are encoded by the genes NTRK1/2/3. TRK fusions are oncogenic drivers of various...

Lung Cancer Leading the Charge for Tumor-Agnostic Targeted Therapies

By Robert C. Doebele, MD, PhD Posted: December 11, 2019 Early in the drug development of targeted therapies, specific oncogene mutations were often associated with a...

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