Tag: larotrectinib
TRK Inhibition in TRK Fusion–Positive Lung Cancers
By Alexander Drilon, MD
Posted: February 12, 2020
The receptor tyrosine kinases TRKA/B/C are encoded by the genes NTRK1/2/3. TRK fusions are oncogenic drivers of various...
Lung Cancer Leading the Charge for Tumor-Agnostic Targeted Therapies
By Robert C. Doebele, MD, PhD
Posted: December 11, 2019
Early in the drug development of targeted therapies, specific oncogene mutations were often associated with a...