Tag: entrectinib
Stunning Progress Achieved in Lung Cancer Treatment Over the Last Decade
By Kara Nyberg, PhD
Posted: April 16, 2020
After decades of failed clinical trials and persistently dismal lung cancer survival outcomes, the 2010s breathed new life...
TRK Inhibition in TRK Fusion–Positive Lung Cancers
By Alexander Drilon, MD
Posted: February 12, 2020
The receptor tyrosine kinases TRKA/B/C are encoded by the genes NTRK1/2/3. TRK fusions are oncogenic drivers of various...
Lung Cancer Leading the Charge for Tumor-Agnostic Targeted Therapies
By Robert C. Doebele, MD, PhD
Posted: December 11, 2019
Early in the drug development of targeted therapies, specific oncogene mutations were often associated with a...